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Because of these possible irritant effects and a potential for worsening of the underlying disease, caution should be used when fosamax is verapamil isoptin to patients with active upper gastrointestinal problems such as known barretts esophagus, dysphagia, other esophageal diseases, gastritis, duodenitis, or ulcers .
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Even dosing with orange juice or coffee has been shown to markedly reduce the absorption of fosamax see clinical pharmacology 12.
Patients should be instructed that if they miss a dose of fosamax once weekly, they should take one tablet on the morning after they remember.
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